Entity Details

Primary name GAK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14976
EntryNameGAK_HUMAN
FullNameCyclin-G-associated kinase
TaxID9606
Evidenceevidence at protein level
Length1311
SequenceStatuscomplete
DateCreated2001-08-29
DateModified2021-06-02

Ontological Relatives

GenesGAK

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0006898 receptor-mediated endocytosis
GO:0007029 endoplasmic reticulum organization
GO:0007030 Golgi organization
GO:0007049 cell cycle
GO:0010977 negative regulation of neuron projection development
GO:0016020 membrane
GO:0016191 synaptic vesicle uncoating
GO:0030276 clathrin binding
GO:0030332 cyclin binding
GO:0031982 vesicle
GO:0034067 protein localization to Golgi apparatus
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0051087 chaperone binding
GO:0061024 membrane organization
GO:0072318 clathrin coat disassembly
GO:0072583 clathrin-dependent endocytosis
GO:0072659 protein localization to plasma membrane
GO:0090160 Golgi to lysosome transport
GO:0098793 presynapse
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1905224 clathrin-coated pit assembly

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001623 DnaJ domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR014020 Tensin phosphatase, C2 domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR029023 Tensin-type phosphatase domainDomainDomain
IPR036869 Chaperone J-domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule