Entity Details

Primary name PER2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15055
EntryNamePER2_HUMAN
FullNamePeriod circadian protein homolog 2
TaxID9606
Evidenceevidence at protein level
Length1255
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesPER2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0001222 transcription corepressor binding
GO:0002931 response to ischemia
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005978 glycogen biosynthetic process
GO:0006094 gluconeogenesis
GO:0006631 fatty acid metabolic process
GO:0007623 circadian rhythm
GO:0019229 regulation of vasoconstriction
GO:0019249 lactate biosynthetic process
GO:0031397 negative regulation of protein ubiquitination
GO:0032922 circadian regulation of gene expression
GO:0042752 regulation of circadian rhythm
GO:0042754 negative regulation of circadian rhythm
GO:0043153 entrainment of circadian clock by photoperiod
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048471 perinuclear region of cytoplasm
GO:0050767 regulation of neurogenesis
GO:0050796 regulation of insulin secretion
GO:0050872 white fat cell differentiation
GO:0051726 regulation of cell cycle
GO:0051946 regulation of glutamate uptake involved in transmission of nerve impulse
GO:0070345 negative regulation of fat cell proliferation
GO:0070932 histone H3 deacetylation
GO:0097167 circadian regulation of translation
GO:0120162 positive regulation of cold-induced thermogenesis
GO:2000678 negative regulation of transcription regulatory region DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR013655 PAS fold-3DomainDomain
IPR022728 Period circadian-like, C-terminalDomainDomain
IPR035965 PAS domain superfamilyFamilyHomologous superfamily

Diseases

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