Entity Details

Primary name PLCA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99943
EntryNamePLCA_HUMAN
FullName1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
TaxID9606
Evidenceevidence at protein level
Length283
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesAGPAT1

GO terms

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GOName
GO:0001819 positive regulation of cytokine production
GO:0001961 positive regulation of cytokine-mediated signaling pathway
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006644 phospholipid metabolic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016024 CDP-diacylglycerol biosynthetic process
GO:0031325 positive regulation of cellular metabolic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR002123 Phospholipid/glycerol acyltransferaseDomainDomain
IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferaseDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PLCA_HUMANMEOX2_HUMANBioGRID, IntAct25416956 details
PLCA_HUMANRENT2_HUMANBioGRID15231747 details