Entity Details

Primary name GRM6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15303
EntryNameGRM6_HUMAN
FullNameMetabotropic glutamate receptor 6
TaxID9606
Evidenceevidence at protein level
Length877
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesGRM6

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007216 G protein-coupled glutamate receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007626 locomotory behavior
GO:0008066 glutamate receptor activity
GO:0009584 detection of visible light
GO:0030425 dendrite
GO:0035841 new growing cell tip
GO:0042803 protein homodimerization activity
GO:0045202 synapse
GO:0050908 detection of light stimulus involved in visual perception
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060041 retina development in camera-type eye
GO:0090280 positive regulation of calcium ion import

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Endoplasmic reticulum membrane
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR000112 GPCR, family 3, metabotropic glutamate receptor 6FamilyFamily
IPR000162 GPCR, family 3, metabotropic glutamate receptorFamilyFamily
IPR000337 GPCR, family 3FamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR011500 GPCR, family 3, nine cysteines domainDomainDomain
IPR017978 GPCR family 3, C-terminalDomainDomain
IPR017979 GPCR, family 3, conserved siteSiteConserved site
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily
IPR038550 GPCR, family 3, nine cysteines domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
GRM6_HUMANCLK1_HUMANBioGRID26167880 details
GRM6_HUMANGNAO_HUMANHPRD11124982 details