Entity Details

Primary name LACRT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9GZZ8
EntryNameLACRT_HUMAN
FullNameExtracellular glycoprotein lacritin
TaxID9606
Evidenceevidence at protein level
Length138
SequenceStatuscomplete
DateCreated2003-07-25
DateModified2021-06-02

Ontological Relatives

GenesLACRT

GO terms

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GOName
GO:0001968 fibronectin binding
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006473 protein acetylation
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0010669 epithelial structure maintenance
GO:0016239 positive regulation of macroautophagy
GO:0019722 calcium-mediated signaling
GO:0030141 secretory granule
GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0033173 calcineurin-NFAT signaling cascade
GO:0034067 protein localization to Golgi apparatus
GO:0042742 defense response to bacterium
GO:0043066 negative regulation of apoptotic process
GO:0043237 laminin-1 binding
GO:0047485 protein N-terminus binding
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850 positive regulation of calcium-mediated signaling
GO:0051047 positive regulation of secretion
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0070075 tear secretion
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR033530 Extracellular glycoprotein lacritinFamilyFamily
IPR043557 Dermcidin/LacritinFamilyFamily

Diseases

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Interactions

6 interactions