Entity Details

Primary name ADA19_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H013
EntryNameADA19_HUMAN
FullNameDisintegrin and metalloproteinase domain-containing protein 19
TaxID9606
Evidenceevidence at protein level
Length955
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesADAM19

GO terms

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GOName
GO:0001890 placenta development
GO:0004222 metalloendopeptidase activity
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006509 membrane protein ectodomain proteolysis
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0017124 SH3 domain binding
GO:0030198 extracellular matrix organization
GO:0042987 amyloid precursor protein catabolic process
GO:0046872 metal ion binding
GO:0062023 collagen-containing extracellular matrix
GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR001762 Disintegrin domainDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR006586 ADAM, cysteine-rich domainDomainDomain
IPR018358 Disintegrin, conserved siteSiteConserved site
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR033596 ADAM19 peptidaseFamilyFamily
IPR034027 Reprolysin domain, adamalysin-typeDomainDomain
IPR036436 Disintegrin domain superfamilyFamilyHomologous superfamily

Diseases

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