Entity Details

Primary name BCAT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15382
EntryNameBCAT2_HUMAN
FullNameBranched-chain-amino-acid aminotransferase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length392
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesBCAT2

GO terms

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GOName
GO:0004084 branched-chain-amino-acid transaminase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009083 branched-chain amino acid catabolic process
GO:0009098 leucine biosynthetic process
GO:0009099 valine biosynthetic process
GO:0050048 L-leucine:2-oxoglutarate aminotransferase activity
GO:0052654 L-leucine transaminase activity
GO:0052655 L-valine transaminase activity
GO:0052656 L-isoleucine transaminase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion

Domains

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DomainNameCategoryType
IPR001544 Aminotransferase class IVFamilyFamily
IPR005786 Branched-chain amino acid aminotransferase IIFamilyFamily
IPR018300 Aminotransferase, class IV, conserved siteSiteConserved site
IPR033939 Branched-chain aminotransferaseFamilyFamily
IPR036038 Aminotransferase-like, PLP-dependent enzymesFamilyHomologous superfamily
IPR043131 Branched-chain-amino-acid aminotransferase-like, N-terminalFamilyHomologous superfamily
IPR043132 Branched-chain-amino-acid aminotransferase-like, C-terminalFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule
DB00149 LeucineDrugbanksmall molecule
DB00167 IsoleucineDrugbanksmall molecule
DB02142 Pyridoxamine-5'-PhosphateDrugbanksmall molecule
DB02635 N-[O-Phosphono-Pyridoxyl]-IsoleucineDrugbanksmall molecule
DB04074 alpha-KetoisovalerateDrugbanksmall molecule