Entity Details

Primary name SOX17_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H6I2
EntryNameSOX17_HUMAN
FullNameTranscription factor SOX-17
TaxID9606
Evidenceevidence at protein level
Length414
SequenceStatuscomplete
DateCreated2002-10-10
DateModified2021-06-02

Ontological Relatives

GenesSOX17

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001656 metanephros development
GO:0001706 endoderm formation
GO:0001714 endodermal cell fate specification
GO:0001828 inner cell mass cellular morphogenesis
GO:0001947 heart looping
GO:0003142 cardiogenic plate morphogenesis
GO:0003143 embryonic heart tube morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003308 negative regulation of Wnt signaling pathway involved in heart development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007283 spermatogenesis
GO:0007493 endodermal cell fate determination
GO:0007507 heart development
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0009653 anatomical structure morphogenesis
GO:0010628 positive regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0021903 rostrocaudal neural tube patterning
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030154 cell differentiation
GO:0030308 negative regulation of cell growth
GO:0031648 protein destabilization
GO:0035050 embryonic heart tube development
GO:0042074 cell migration involved in gastrulation
GO:0045597 positive regulation of cell differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045995 regulation of embryonic development
GO:0048617 embryonic foregut morphogenesis
GO:0048866 stem cell fate specification
GO:0050821 protein stabilization
GO:0060214 endocardium formation
GO:0060913 cardiac cell fate determination
GO:0060914 heart formation
GO:0060956 endocardial cell differentiation
GO:0061009 common bile duct development
GO:0061010 gall bladder development
GO:0061031 endodermal digestive tract morphogenesis
GO:0072091 regulation of stem cell proliferation
GO:0072189 ureter development
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1990830 cellular response to leukemia inhibitory factor
GO:2000035 regulation of stem cell division
GO:2000043 regulation of cardiac cell fate specification

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR021934 Sox, C-terminalDomainDomain
IPR033392 Sox 7/17/18, central domainDomainDomain
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SOX17_HUMANAPBA3_HUMANUniProt26948053 details
SOX17_HUMANCTNB1_HUMANbhf-ucl, HPRD15163629 17875931 details