Entity Details

Primary name DHX33_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H6R0
EntryNameDHX33_HUMAN
FullNameATP-dependent RNA helicase DHX33
TaxID9606
Evidenceevidence at protein level
Length707
SequenceStatuscomplete
DateCreated2005-11-22
DateModified2021-06-02

Ontological Relatives

GenesDHX33

GO terms

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GOName
GO:0000182 rDNA binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0003725 double-stranded RNA binding
GO:0003729 mRNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006413 translational initiation
GO:0016787 hydrolase activity
GO:0032481 positive regulation of type I interferon production
GO:0043023 ribosomal large subunit binding
GO:0043410 positive regulation of MAPK cascade
GO:0045943 positive regulation of transcription by RNA polymerase I
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0072559 NLRP3 inflammasome complex
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Inflammasome
Nucleus

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteSiteConserved site
IPR007502 Helicase-associated domainDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR011709 Domain of unknown function DUF1605DomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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