Entity Details

Primary name ARHG3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR81
EntryNameARHG3_HUMAN
FullNameRho guanine nucleotide exchange factor 3
TaxID9606
Evidenceevidence at protein level
Length526
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesARHGEF3

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007266 Rho protein signal transduction
GO:0035025 positive regulation of Rho protein signal transduction
GO:0043065 positive regulation of apoptotic process
GO:0051056 regulation of small GTPase mediated signal transduction

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR044129 Rho guanine nucleotide exchange factor 3, PH domainDomainDomain

Diseases

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