Entity Details

Primary name KCNQ5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR82
EntryNameKCNQ5_HUMAN
FullNamePotassium voltage-gated channel subfamily KQT member 5
TaxID9606
Evidenceevidence at protein level
Length932
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesKCNQ5

GO terms

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GOName
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005516 calmodulin binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
GO:0030118 clathrin coat
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003937 Potassium channel, voltage dependent, KCNQFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminalDomainDomain
IPR028325 Voltage-gated potassium channelFamilyFamily
IPR043238 Potassium voltage-gated channel subfamily KQT member 5FamilyFamily

Diseases

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Disease IDSourceNameDescription
617601 OMIMMental retardation, autosomal dominant 46 (MRD46)A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRD46 patients manifest developmental delay and mild to moderate intellectual disability. The disease is caused by variants affecting the gene represented in this entry.

Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB00996 GabapentinDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB04953 EzogabineDrugbanksmall molecule
DB06089 ICA-105665Drugbanksmall molecule