Entity Details

Primary name PLEK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NYT0
EntryNamePLEK2_HUMAN
FullNamePleckstrin-2
TaxID9606
Evidenceevidence at protein level
Length353
SequenceStatuscomplete
DateCreated2002-05-10
DateModified2021-06-02

Ontological Relatives

GenesPLEK2

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0031258 lamellipodium membrane
GO:0031532 actin cytoskeleton reorganization
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0035556 intracellular signal transduction
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
GO:0120034 positive regulation of plasma membrane bounded cell projection assembly

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000591 DEP domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037369 Pleckstrin-2, DEP domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PLEK2_HUMANEGFR_HUMANBioGRID31182136 details