Entity Details

Primary name IRPL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZN1
EntryNameIRPL1_HUMAN
FullNameInterleukin-1 receptor accessory protein-like 1
TaxID9606
Evidenceevidence at protein level
Length696
SequenceStatuscomplete
DateCreated2003-08-22
DateModified2021-06-02

Ontological Relatives

GenesIL1RAPL1

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007165 signal transduction
GO:0009986 cell surface
GO:0010975 regulation of neuron projection development
GO:0016021 integral component of membrane
GO:0030182 neuron differentiation
GO:0030424 axon
GO:0030425 dendrite
GO:0045211 postsynaptic membrane
GO:0045920 negative regulation of exocytosis
GO:0050135 NAD(P)+ nucleosidase activity
GO:0050775 positive regulation of dendrite morphogenesis
GO:0051965 positive regulation of synapse assembly
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0071345 cellular response to cytokine stimulus
GO:0097105 presynaptic membrane assembly
GO:0098978 glutamatergic synapse
GO:0099175 regulation of postsynapse organization
GO:0099545 trans-synaptic signaling by trans-synaptic complex
GO:1905606 regulation of presynapse assembly

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000157 Toll/interleukin-1 receptor homology (TIR) domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015621 Interleukin-1 receptor familyFamilyFamily
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR041416 IL-1Ra-like, immunoglobulin domainDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
IRPL1_HUMANNCS1_HUMANBioGRID, HPRD12783849 details
IRPL1_HUMANRHG22_HUMANBioGRID21926414 details
IRPL1_HUMANPTPRD_HUMANBioGRID21926414 details