Entity Details

Primary name FZD10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9ULW2
EntryNameFZD10_HUMAN
FullNameFrizzled-10
TaxID9606
Evidenceevidence at protein level
Length581
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFZD10

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0017147 Wnt-protein binding
GO:0030182 neuron differentiation
GO:0032956 regulation of actin cytoskeleton organization
GO:0034260 negative regulation of GTPase activity
GO:0038031 non-canonical Wnt signaling pathway via JNK cascade
GO:0042813 Wnt-activated receptor activity
GO:0043507 positive regulation of JUN kinase activity
GO:0043547 positive regulation of GTPase activity
GO:0060070 canonical Wnt signaling pathway
GO:0071300 cellular response to retinoic acid

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR026549 Frizzled-10FamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily

Diseases

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