Entity Details

Primary name FARP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y4F1
EntryNameFARP1_HUMAN
FullNameFERM, ARHGEF and pleckstrin domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length1045
SequenceStatuscomplete
DateCreated2006-04-18
DateModified2021-06-02

Ontological Relatives

GenesFARP1

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0007416 synapse assembly
GO:0008092 cytoskeletal protein binding
GO:0010923 negative regulation of phosphatase activity
GO:0030175 filopodium
GO:0030425 dendrite
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0043197 dendritic spine
GO:0048813 dendrite morphogenesis

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR000299 FERM domainDomainDomain
IPR000798 Ezrin/radixin/moesin-likeFamilyFamily
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014352 FERM/acyl-CoA-binding protein superfamilyFamilyHomologous superfamily
IPR014847 FERM adjacent (FA)DomainDomain
IPR018979 FERM, N-terminalDomainDomain
IPR018980 FERM, C-terminal PH-like domainDomainDomain
IPR019747 FERM conserved siteSiteConserved site
IPR019748 FERM central domainDomainDomain
IPR019749 Band 4.1 domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR035963 FERM superfamily, second domainFamilyHomologous superfamily
IPR041788 FARP1/FARP2/FRMD7, FERM domain C-lobeDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
FARP1_HUMANPP1A_HUMANUniProt19389623 details
FARP1_HUMANPIHD1_HUMANBioGRID, IntAct32296183 details
FARP1_HUMANRBM47_HUMANBioGRID29395067 details