Entity Details

Primary name JAM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y624
EntryNameJAM1_HUMAN
FullNameJunctional adhesion molecule A
TaxID9606
Evidenceevidence at protein level
Length299
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesF11R

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0001817 regulation of cytokine production
GO:0005178 integrin binding
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005923 bicellular tight junction
GO:0006954 inflammatory response
GO:0007159 leukocyte cell-cell adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0008360 regulation of cell shape
GO:0009314 response to radiation
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030165 PDZ domain binding
GO:0030198 extracellular matrix organization
GO:0031032 actomyosin structure organization
GO:0031410 cytoplasmic vesicle
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0034260 negative regulation of GTPase activity
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035633 maintenance of blood-brain barrier
GO:0035683 memory T cell extravasation
GO:0036057 slit diaphragm
GO:0042803 protein homodimerization activity
GO:0043547 positive regulation of GTPase activity
GO:0045296 cadherin binding
GO:0045777 positive regulation of blood pressure
GO:0050892 intestinal absorption
GO:0050900 leukocyte migration
GO:0051493 regulation of cytoskeleton organization
GO:0051497 negative regulation of stress fiber assembly
GO:0070062 extracellular exosome
GO:0070160 tight junction
GO:0070830 bicellular tight junction assembly
GO:0071260 cellular response to mechanical stimulus
GO:0072659 protein localization to plasma membrane
GO:0090557 establishment of endothelial intestinal barrier
GO:0090559 regulation of membrane permeability
GO:0098609 cell-cell adhesion
GO:1901731 positive regulation of platelet aggregation
GO:1902396 protein localization to bicellular tight junction
GO:1903142 positive regulation of establishment of endothelial barrier
GO:2000249 regulation of actin cytoskeleton reorganization
GO:2000810 regulation of bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR042456 Junctional adhesion molecule AFamilyFamily

Diseases

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