Entity Details

Primary name PTC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6C5
EntryNamePTC2_HUMAN
FullNameProtein patched homolog 2
TaxID9606
Evidenceevidence at protein level
Length1203
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesPTCH2

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0001709 cell fate determination
GO:0005119 smoothened binding
GO:0005886 plasma membrane
GO:0007224 smoothened signaling pathway
GO:0008158 hedgehog receptor activity
GO:0009957 epidermal cell fate specification
GO:0016021 integral component of membrane
GO:0042633 hair cycle
GO:0043588 skin development
GO:0045606 positive regulation of epidermal cell differentiation
GO:0045879 negative regulation of smoothened signaling pathway
GO:0097108 hedgehog family protein binding

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000731 Sterol-sensing domainDomainDomain
IPR003392 Protein patched/dispatchedFamilyFamily
IPR004766 Transmembrane receptor, patchedFamilyFamily

Diseases

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Interactions

4 interactions