Entity Details

Primary name PCLO_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6V0
EntryNamePCLO_HUMAN
FullNameProtein piccolo
TaxID9606
Evidenceevidence at protein level
Length5142
SequenceStatuscomplete
DateCreated2002-10-19
DateModified2021-06-02

Ontological Relatives

GenesPCLO

GO terms

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GOName
GO:0005509 calcium ion binding
GO:0005522 profilin binding
GO:0005544 calcium-dependent phospholipid binding
GO:0005856 cytoskeleton
GO:0007010 cytoskeleton organization
GO:0014069 postsynaptic density
GO:0016079 synaptic vesicle exocytosis
GO:0017157 regulation of exocytosis
GO:0019933 cAMP-mediated signaling
GO:0030073 insulin secretion
GO:0030424 axon
GO:0035418 protein localization to synapse
GO:0045202 synapse
GO:0048788 cytoskeleton of presynaptic active zone
GO:0070062 extracellular exosome
GO:0097091 synaptic vesicle clustering
GO:0098882 structural constituent of presynaptic active zone
GO:0098978 glutamatergic synapse
GO:0098982 GABA-ergic synapse
GO:0099526 presynapse to nucleus signaling pathway
GO:1904071 presynaptic active zone assembly

Subcellular Location

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Subcellular Location
Cell junction

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR008899 Zinc finger, piccolo-typeDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR030629 Protein piccoloFamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR042720 Piccolo, FYVE-related domain 1DomainDomain

Diseases

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Interactions

4 interactions