Entity Details

Primary name DSCAM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60469
EntryNameDSCAM_HUMAN
FullNameDown syndrome cell adhesion molecule
TaxID9606
Evidenceevidence at protein level
Length2012
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesDSCAM

GO terms

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GOName
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007162 negative regulation of cell adhesion
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007416 synapse assembly
GO:0007626 locomotory behavior
GO:0010842 retina layer formation
GO:0016020 membrane
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0042327 positive regulation of phosphorylation
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0048813 dendrite morphogenesis
GO:0048842 positive regulation of axon extension involved in axon guidance
GO:0060060 post-embryonic retina morphogenesis in camera-type eye
GO:0060219 camera-type eye photoreceptor cell differentiation
GO:0070593 dendrite self-avoidance
GO:0098632 cell-cell adhesion mediator activity
GO:1990782 protein tyrosine kinase binding
GO:1990890 netrin receptor binding

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Secreted

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR033027 Down syndrome cell adhesion molecule, metazoanFamilyFamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR043204 Basigin-likeFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DSCAM_HUMANPIHD2_HUMANBioGRID, IntAct32296183 details
DSCAM_HUMANPAK1_HUMANHPRD15169762 details