Entity Details

Primary name CTNS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60931
EntryNameCTNS_HUMAN
FullNameCystinosin
TaxID9606
Evidenceevidence at protein level
Length367
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesCTNS

GO terms

Show/Hide Table
GOName
GO:0002088 lens development in camera-type eye
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0005774 vacuolar membrane
GO:0005886 plasma membrane
GO:0006520 cellular amino acid metabolic process
GO:0006749 glutathione metabolic process
GO:0006811 ion transport
GO:0007420 brain development
GO:0007616 long-term memory
GO:0007625 grooming behavior
GO:0007628 adult walking behavior
GO:0008542 visual learning
GO:0010730 negative regulation of hydrogen peroxide biosynthetic process
GO:0010918 positive regulation of mitochondrial membrane potential
GO:0015031 protein transport
GO:0015184 L-cystine transmembrane transporter activity
GO:0015295 solute:proton symporter activity
GO:0015811 L-cystine transport
GO:0016021 integral component of membrane
GO:0033162 melanosome membrane
GO:0042438 melanin biosynthetic process
GO:0042470 melanosome
GO:0043231 intracellular membrane-bounded organelle
GO:0045111 intermediate filament cytoskeleton
GO:0046034 ATP metabolic process
GO:0048021 regulation of melanin biosynthetic process
GO:0050890 cognition
GO:0055085 transmembrane transport
GO:0070062 extracellular exosome
GO:1904263 positive regulation of TORC1 signaling

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Lysosome membrane
Melanosome membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR005282 Lysosomal cystine transporterFamilyFamily
IPR006603 PQ-loop repeatRepeatRepeat

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00138 CystineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CTNS_HUMANGNMT_HUMANBioGRID, IntAct32296183 details