Entity Details

Primary name LRP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75074
EntryNameLRP3_HUMAN
FullNameLow-density lipoprotein receptor-related protein 3
TaxID9606
Evidenceevidence at transcript level
Length770
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesLRP3

GO terms

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GOName
GO:0005905 clathrin-coated pit
GO:0006898 receptor-mediated endocytosis
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0016021 integral component of membrane
GO:0045599 negative regulation of fat cell differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0150104 transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000859 CUB domainDomainDomain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
LRP3_HUMANGGA2_HUMANHPRD, MINT11390366 details
LRP3_HUMANGGA1_HUMANBioGRID, HPRD, MINT11390366 details
LRP3_HUMANMTR1A_HUMANBioGRID, IntAct26514267 details