Entity Details

Primary name ZO3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95049
EntryNameZO3_HUMAN
FullNameTight junction protein ZO-3
TaxID9606
Evidenceevidence at protein level
Length919
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesTJP3

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005923 bicellular tight junction
GO:0030054 cell junction
GO:0035633 maintenance of blood-brain barrier
GO:0045216 cell-cell junction organization
GO:0050839 cell adhesion molecule binding
GO:0090557 establishment of endothelial intestinal barrier
GO:0098609 cell-cell adhesion
GO:0150105 protein localization to cell-cell junction
GO:1905605 positive regulation of blood-brain barrier permeability

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR005417 Tight junction protein ZOFamilyFamily
IPR005420 Tight junction protein ZO-3FamilyFamily
IPR008144 Guanylate kinase-like domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions