Entity Details

Primary name GDF11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95390
EntryNameGDF11_HUMAN
FullNameGrowth/differentiation factor 11
TaxID9606
Evidenceevidence at protein level
Length407
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesGDF11

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001656 metanephros development
GO:0001657 ureteric bud development
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0007399 nervous system development
GO:0007498 mesoderm development
GO:0008083 growth factor activity
GO:0008285 negative regulation of cell population proliferation
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0021512 spinal cord anterior/posterior patterning
GO:0031016 pancreas development
GO:0032991 protein-containing complex
GO:0043231 intracellular membrane-bounded organelle
GO:0045665 negative regulation of neuron differentiation
GO:0048469 cell maturation
GO:0048593 camera-type eye morphogenesis
GO:0060021 roof of mouth development
GO:0060395 SMAD protein signal transduction

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001111 TGF-beta, propeptideDomainDomain
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

3 interactions