Entity Details

Primary name CER1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95813
EntryNameCER1_HUMAN
FullNameCerberus
TaxID9606
Evidenceevidence at protein level
Length267
SequenceStatuscomplete
DateCreated2005-04-12
DateModified2021-06-02

Ontological Relatives

GenesCER1

GO terms

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GOName
GO:0001657 ureteric bud development
GO:0003419 growth plate cartilage chondrocyte proliferation
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007369 gastrulation
GO:0007399 nervous system development
GO:0008285 negative regulation of cell population proliferation
GO:0009948 anterior/posterior axis specification
GO:0009952 anterior/posterior pattern specification
GO:0016015 morphogen activity
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030282 bone mineralization
GO:0030514 negative regulation of BMP signaling pathway
GO:0032926 negative regulation of activin receptor signaling pathway
GO:0035582 sequestering of BMP in extracellular matrix
GO:0036122 BMP binding
GO:0038098 sequestering of BMP from receptor via BMP binding
GO:0042074 cell migration involved in gastrulation
GO:0042803 protein homodimerization activity
GO:0048263 determination of dorsal identity
GO:0061371 determination of heart left/right asymmetry
GO:0071276 cellular response to cadmium ion
GO:0071773 cellular response to BMP stimulus
GO:1900176 negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
GO:2000381 negative regulation of mesoderm development

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR004133 DANDomainDomain
IPR006207 Cystine knot, C-terminalDomainDomain
IPR016860 CerberusFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CER1_HUMANCER1_HUMANHPRD9501024 details