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Entity Details
Primary name
PAI2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P05120
EntryName
PAI2_HUMAN
FullName
Plasminogen activator inhibitor 2
TaxID
9606
Evidence
evidence at protein level
Length
415
SequenceStatus
complete
DateCreated
1987-08-13
DateModified
2021-06-02
Ontological Relatives
Genes
SERPINB2
GO terms
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GO
Name
GO:0004867
serine-type endopeptidase inhibitor activity
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0005737
cytoplasm
GO:0005886
plasma membrane
GO:0010951
negative regulation of endopeptidase activity
GO:0035722
interleukin-12-mediated signaling pathway
GO:0042060
wound healing
GO:0042730
fibrinolysis
GO:0043066
negative regulation of apoptotic process
Subcellular Location
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Subcellular Location
Cytoplasm
Secreted
Domains
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Domain
Name
Category
Type
IPR000215
Serpin family
Family
Family
IPR015556
Plasminogen activator inhibitor-2
Family
Family
IPR023795
Serpin, conserved site
Site
Conserved site
IPR023796
Serpin domain
Domain
Domain
IPR036186
Serpin superfamily
Family
Homologous superfamily
IPR042178
Serpin superfamily, domain 1
Family
Homologous superfamily
IPR042185
Serpin superfamily, domain 2
Family
Homologous superfamily
Diseases
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Drugs
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Drug
Name
Source
Type
DB00013
Urokinase
Drugbank
biotech
DB00031
Tenecteplase
Drugbank
biotech
DB06245
Lanoteplase
Drugbank
biotech
Interactions
10 interactions
Interactor
Partner
Sources
Publications
Link
PAI2_HUMAN
RB_HUMAN
BioGRID, HPRD
12944478
16397580
details
PAI2_HUMAN
UROK_HUMAN
BioGRID, HPRD
2161846
2166055
8388810
details
PAI2_HUMAN
PSB1_HUMAN
BioGRID, HPRD
14732874
details
PAI2_HUMAN
PRP8_HUMAN
BioGRID, HPRD
15346200
details
PAI2_HUMAN
A4_HUMAN
BioGRID
21832049
details
PAI2_HUMAN
CDC42_HUMAN
BioGRID
31478661
details
PAI2_HUMAN
UBE3A_HUMAN
BioGRID
32545848
details
PAI2_HUMAN
IRF3_HUMAN
HPRD
12883638
details
PAI2_HUMAN
RBL2_HUMAN
BioGRID
16397580
details
PAI2_HUMAN
PAI2_HUMAN
HPRD
12682008
details
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