Entity Details

Primary name ECP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12724
EntryNameECP_HUMAN
FullNameEosinophil cationic protein
TaxID9606
Evidenceevidence at protein level
Length160
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesRNASE3

GO terms

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GOName
GO:0001530 lipopolysaccharide binding
GO:0002227 innate immune response in mucosa
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004540 ribonuclease activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006401 RNA catabolic process
GO:0006935 chemotaxis
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0035578 azurophil granule lumen
GO:0043152 induction of bacterial agglutination
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001427 Pancreatic ribonucleaseFamilyFamily
IPR023411 Ribonuclease A, active siteSiteActive site
IPR023412 Ribonuclease A-domainDomainDomain
IPR036816 Ribonuclease A-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01411 PranlukastDrugbanksmall molecule
DB02098 Adenosine-2'-5'-DiphosphateDrugbanksmall molecule
DB04272 Citric acidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink