Entity Details

Primary name DCAM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17707
EntryNameDCAM_HUMAN
FullNameS-adenosylmethionine decarboxylase proenzyme
TaxID9606
Evidenceevidence at protein level
Length334
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesAMD1

GO terms

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GOName
GO:0004014 adenosylmethionine decarboxylase activity
GO:0005829 cytosol
GO:0006557 S-adenosylmethioninamine biosynthetic process
GO:0006595 polyamine metabolic process
GO:0006597 spermine biosynthetic process
GO:0008295 spermidine biosynthetic process
GO:0019810 putrescine binding
GO:0042802 identical protein binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001985 S-adenosylmethionine decarboxylaseFamilyFamily
IPR016067 S-adenosylmethionine decarboxylase, coreFamilyHomologous superfamily
IPR018166 S-adenosylmethionine decarboxylase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00118 AdemetionineDrugbanksmall molecule
DB01917 PutrescineDrugbanksmall molecule
DB08163 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosineDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
DCAM_HUMANHSPB1_HUMANBioGRID, IntAct25277244 details
DCAM_HUMANDCAM_HUMANBioGRID, HPRD, IntAct10378277 11583147 11583148 12600205 32296183 details
DCAM_HUMANTHAP4_HUMANBioGRID, IntAct32296183 details