Entity Details

Primary name 5NTD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21589
EntryName5NTD_HUMAN
FullName5'-nucleotidase
TaxID9606
Evidenceevidence at protein level
Length574
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesNT5E

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006195 purine nucleotide catabolic process
GO:0006196 AMP catabolic process
GO:0006259 DNA metabolic process
GO:0007159 leukocyte cell-cell adhesion
GO:0008253 5'-nucleotidase activity
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0019674 NAD metabolic process
GO:0031225 anchored component of membrane
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0046032 ADP catabolic process
GO:0046086 adenosine biosynthetic process
GO:0046135 pyrimidine nucleoside catabolic process
GO:0046872 metal ion binding
GO:0050728 negative regulation of inflammatory response
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR004843 Calcineurin-like phosphoesterase domain, ApaH typeDomainDomain
IPR006146 5'-Nucleotidase, conserved siteSiteConserved site
IPR006179 5'-Nucleotidase/apyraseFamilyFamily
IPR008334 5'-Nucleotidase, C-terminalDomainDomain
IPR029052 Metallo-dependent phosphatase-likeFamilyHomologous superfamily
IPR036907 5'-Nucleotidase, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00806 PentoxifyllineDrugbanksmall molecule
DB00987 CytarabineDrugbanksmall molecule