Entity Details

Primary name OSBP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22059
EntryNameOSBP1_HUMAN
FullNameOxysterol-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length807
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesOSBP

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006699 bile acid biosynthetic process
GO:0008142 oxysterol binding
GO:0015248 sterol transporter activity
GO:0015918 sterol transport
GO:0016020 membrane
GO:0019904 protein domain specific binding
GO:0030054 cell junction
GO:0032367 intracellular cholesterol transport
GO:0032934 sterol binding
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0097038 perinuclear endoplasmic reticulum
GO:0120015 sterol transfer activity
GO:1904411 positive regulation of secretory granule organization

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Golgi apparatus
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR000648 Oxysterol-binding proteinFamilyFamily
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR018494 Oxysterol-binding protein, conserved siteSiteConserved site
IPR037239 Oxysterol-binding protein superfamilyFamilyHomologous superfamily

Diseases

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