Entity Details

Primary name CNTFR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26992
EntryNameCNTFR_HUMAN
FullNameCiliary neurotrophic factor receptor subunit alpha
TaxID9606
Evidenceevidence at protein level
Length372
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesCNTFR

GO terms

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GOName
GO:0001967 suckling behavior
GO:0003360 brainstem development
GO:0004896 cytokine receptor activity
GO:0004897 ciliary neurotrophic factor receptor activity
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0007548 sex differentiation
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0016324 apical plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019898 extrinsic component of membrane
GO:0019955 cytokine binding
GO:0031225 anchored component of membrane
GO:0043235 receptor complex
GO:0043524 negative regulation of neuron apoptotic process
GO:0060538 skeletal muscle organ development
GO:0070110 ciliary neurotrophic factor receptor complex
GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
GO:0097059 CNTFR-CLCF1 complex

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003530 Long hematopoietin receptor, soluble alpha chain, conserved siteSiteConserved site
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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