Entity Details

Primary name NMT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30419
EntryNameNMT1_HUMAN
FullNameGlycylpeptide N-tetradecanoyltransferase 1
TaxID9606
Evidenceevidence at protein level
Length496
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesNMT1

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006499 N-terminal protein myristoylation
GO:0018008 N-terminal peptidyl-glycine N-myristoylation
GO:0019107 myristoyltransferase activity
GO:0019898 extrinsic component of membrane
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0042180 cellular ketone metabolic process
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000903 Myristoyl-CoA:protein N-myristoyltransferaseFamilyFamily
IPR016181 Acyl-CoA N-acyltransferaseFamilyHomologous superfamily
IPR022676 Myristoyl-CoA:protein N-myristoyltransferase, N-terminalDomainDomain
IPR022677 Myristoyl-CoA:protein N-myristoyltransferase, C-terminalDomainDomain
IPR022678 Myristoyl-CoA:protein N-myristoyltransferase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB03062 (1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-MethanoneDrugbanksmall molecule