Search
News
Downloads
About
Help
Contact
Entity Details
Primary name
SCNNA_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P37088
EntryName
SCNNA_HUMAN
FullName
Amiloride-sensitive sodium channel subunit alpha
TaxID
9606
Evidence
evidence at protein level
Length
669
SequenceStatus
complete
DateCreated
1994-10-01
DateModified
2021-06-02
Ontological Relatives
Genes
SCNN1A
GO terms
Show/Hide Table
GO
Name
GO:0001669
acrosomal vesicle
GO:0005737
cytoplasm
GO:0005886
plasma membrane
GO:0005887
integral component of plasma membrane
GO:0015280
ligand-gated sodium channel activity
GO:0016324
apical plasma membrane
GO:0031514
motile cilium
GO:0034220
ion transmembrane transport
GO:0034706
sodium channel complex
GO:0035725
sodium ion transmembrane transport
GO:0050699
WW domain binding
GO:0050891
multicellular organismal water homeostasis
GO:0050896
response to stimulus
GO:0050909
sensory perception of taste
GO:0055078
sodium ion homeostasis
GO:0060170
ciliary membrane
GO:0070062
extracellular exosome
GO:0097228
sperm principal piece
Subcellular Location
Show/Hide Table
Subcellular Location
Apical cell membrane
Cell projection
Cytoplasm
Cytoplasmic granule
Cytoplasmic vesicle
Domains
Show/Hide Table
Domain
Name
Category
Type
IPR001873
Epithelial sodium channel
Family
Family
IPR004724
Epithelial sodium channel, chordates
Family
Family
IPR020903
Epithelial sodium channel, conserved site
Site
Conserved site
Diseases
Show/Hide Table
Drugs
Show/Hide Table
Drug
Name
Source
Type
DB00384
Triamterene
Drugbank
small molecule
DB00594
Amiloride
Drugbank
small molecule
DB14509
Lithium carbonate
Drugbank
small molecule
Interactions
26 interactions
Interactor
Partner
Sources
Publications
Link
SCNNA_HUMAN
NEDD4_HUMAN
BioGRID, HPRD, IntAct, MINT
10212229
10642508
11244092
11359767
12167593
23665454
26685112
28471472
details
SCNNA_HUMAN
SCNNB_HUMAN
BioGRID, HPRD, IntAct
21775436
22526458
27903760
8986818
details
SCNNA_HUMAN
UBC9_HUMAN
BioGRID, HPRD
14556380
details
SCNNA_HUMAN
TS101_HUMAN
BioGRID
14556380
details
SCNNA_HUMAN
NED4L_HUMAN
BioGRID, HPRD
11244092
11802777
12876068
14556380
15328345
16416336
16844684
17502380
18322022
18498246
18701608
26651153
details
SCNNA_HUMAN
SERP1_HUMAN
BioGRID
22526458
details
SCNNA_HUMAN
WWP2_HUMAN
BioGRID, HPRD
12167593
details
SCNNA_HUMAN
ITCH_HUMAN
BioGRID
11244092
details
SCNNA_HUMAN
EPN1_HUMAN
BioGRID
16574660
details
SCNNA_HUMAN
WWP1_HUMAN
BioGRID
14556380
details
SCNNA_HUMAN
COMDA_HUMAN
BioGRID
29997525
details
SCNNA_HUMAN
CSK21_HUMAN
BioGRID
18981174
details
SCNNA_HUMAN
HECW1_HUMAN
BioGRID
11244092
details
SCNNA_HUMAN
STX1A_HUMAN
BioGRID, HPRD
10409621
12562778
14996668
details
SCNNA_HUMAN
SCNNG_HUMAN
BioGRID, HPRD, IntAct
10409621
16423824
21775436
27903760
details
SCNNA_HUMAN
HGS_HUMAN
BioGRID
20675381
details
SCNNA_HUMAN
SCNNA_HUMAN
IntAct
21775436
details
SCNNA_HUMAN
SNX3_HUMAN
BioGRID, HPRD
18632802
details
SCNNA_HUMAN
UBP8_HUMAN
BioGRID
23297398
details
SCNNA_HUMAN
HUWE1_HUMAN
BioGRID
28137758
details
SCNNA_HUMAN
UBP2_HUMAN
BioGRID
18701608
21478478
details
SCNNA_HUMAN
SCNND_HUMAN
IntAct
16423824
details
SCNNA_HUMAN
UBP10_HUMAN
BioGRID, HPRD
18632802
details
SCNNA_HUMAN
HYOU1_HUMAN
BioGRID
23645669
details
SCNNA_HUMAN
AP1M2_HUMAN
BioGRID
16574660
details
SCNNA_HUMAN
DERL1_HUMAN
BioGRID
28137758
details
This website requires cookies in order to function. By using the site you are agreeing to this as outlined in our
Terms of Use
I Agree