Entity Details

Primary name V1AR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP37288
EntryNameV1AR_HUMAN
FullNameVasopressin V1a receptor
TaxID9606
Evidenceevidence at protein level
Length418
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesAVPR1A

GO terms

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GOName
GO:0001992 regulation of systemic arterial blood pressure by vasopressin
GO:0002125 maternal aggressive behavior
GO:0003084 positive regulation of systemic arterial blood pressure
GO:0004930 G protein-coupled receptor activity
GO:0005000 vasopressin receptor activity
GO:0005080 protein kinase C binding
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006091 generation of precursor metabolites and energy
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007621 negative regulation of female receptivity
GO:0007625 grooming behavior
GO:0008015 blood circulation
GO:0008284 positive regulation of cell population proliferation
GO:0010460 positive regulation of heart rate
GO:0014049 positive regulation of glutamate secretion
GO:0014902 myotube differentiation
GO:0017046 peptide hormone binding
GO:0019722 calcium-mediated signaling
GO:0021537 telencephalon development
GO:0030139 endocytic vesicle
GO:0030307 positive regulation of cell growth
GO:0031394 positive regulation of prostaglandin biosynthetic process
GO:0031894 V1A vasopressin receptor binding
GO:0032849 positive regulation of cellular pH reduction
GO:0035176 social behavior
GO:0035815 positive regulation of renal sodium excretion
GO:0042277 peptide binding
GO:0042631 cellular response to water deprivation
GO:0042711 maternal behavior
GO:0042713 sperm ejaculation
GO:0043084 penile erection
GO:0045907 positive regulation of vasoconstriction
GO:0051412 response to corticosterone
GO:0051970 negative regulation of transmission of nerve impulse
GO:0150104 transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001224 Vasopressin V1A receptorFamilyFamily
IPR001817 Vasopressin receptorFamilyFamily
IPR015076 Vasopressin V1 receptor, C-terminalDomainDomain
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00035 DesmopressinDrugbanksmall molecule
DB00067 VasopressinDrugbanksmall molecule
DB00093 FelypressinDrugbanksmall molecule
DB00872 ConivaptanDrugbanksmall molecule
DB02638 TerlipressinDrugbanksmall molecule
DB05452 PH-284Drugbanksmall molecule
DB06212 TolvaptanDrugbanksmall molecule
DB09059 AtosibanDrugbanksmall molecule
DB13929 RelcovaptanDrugbanksmall molecule
DB14642 LypressinDrugbanksmall molecule

Interactions

5 interactions