Entity Details

Primary name V1BR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP47901
EntryNameV1BR_HUMAN
FullNameVasopressin V1b receptor
TaxID9606
Evidenceevidence at protein level
Length424
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesAVPR1B

GO terms

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GOName
GO:0001992 regulation of systemic arterial blood pressure by vasopressin
GO:0004930 G protein-coupled receptor activity
GO:0005000 vasopressin receptor activity
GO:0005080 protein kinase C binding
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0032430 positive regulation of phospholipase A2 activity
GO:0042127 regulation of cell population proliferation
GO:0042277 peptide binding
GO:0043410 positive regulation of MAPK cascade
GO:0045907 positive regulation of vasoconstriction
GO:0060732 positive regulation of inositol phosphate biosynthetic process
GO:0090238 positive regulation of arachidonic acid secretion
GO:0150104 transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000628 Vasopressin V1B receptorFamilyFamily
IPR001817 Vasopressin receptorFamilyFamily
IPR015076 Vasopressin V1 receptor, C-terminalDomainDomain
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00035 DesmopressinDrugbanksmall molecule
DB00067 VasopressinDrugbanksmall molecule
DB02638 TerlipressinDrugbanksmall molecule
DB05452 PH-284Drugbanksmall molecule
DB05455 SR 121463Drugbanksmall molecule
DB09059 AtosibanDrugbanksmall molecule
DB14642 LypressinDrugbanksmall molecule

Interactions

3 interactions