Entity Details

Primary name KIF11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52732
EntryNameKIF11_HUMAN
FullNameKinesin-like protein KIF11
TaxID9606
Evidenceevidence at protein level
Length1056
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesKIF11

GO terms

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GOName
GO:0000278 mitotic cell cycle
GO:0000922 spindle pole
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005819 spindle
GO:0005829 cytosol
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0007018 microtubule-based movement
GO:0007051 spindle organization
GO:0007052 mitotic spindle organization
GO:0007100 mitotic centrosome separation
GO:0008017 microtubule binding
GO:0008574 plus-end-directed microtubule motor activity
GO:0016020 membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 protein kinase binding
GO:0032991 protein-containing complex
GO:0046602 regulation of mitotic centrosome separation
GO:0051301 cell division
GO:0072686 mitotic spindle
GO:0090307 mitotic spindle assembly

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001752 Kinesin motor domainDomainDomain
IPR019821 Kinesin motor domain, conserved siteSiteConserved site
IPR025901 Kinesin-associated microtubule-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03996 3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]PhenolDrugbanksmall molecule
DB04331 MonastrolDrugbanksmall molecule
DB06040 FilanesibDrugbanksmall molecule
DB07064 (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDEDrugbanksmall molecule
DB08032 N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDEDrugbanksmall molecule
DB08033 (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDEDrugbanksmall molecule
DB08037 MK-0731Drugbanksmall molecule
DB08198 [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONEDrugbanksmall molecule
DB08239 (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDEDrugbanksmall molecule
DB08244 (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINEDrugbanksmall molecule
DB08246 (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDEDrugbanksmall molecule
DB08250 (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDEDrugbanksmall molecule