Entity Details

Primary name CLD18_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56856
EntryNameCLD18_HUMAN
FullNameClaudin-18
TaxID9606
Evidenceevidence at protein level
Length261
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesCLDN18

GO terms

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GOName
GO:0005198 structural molecule activity
GO:0005886 plasma membrane
GO:0005923 bicellular tight junction
GO:0007155 cell adhesion
GO:0016021 integral component of membrane
GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0042802 identical protein binding
GO:0045471 response to ethanol
GO:0045779 negative regulation of bone resorption
GO:0048565 digestive tract development
GO:0070830 bicellular tight junction assembly
GO:0071847 TNFSF11-mediated signaling pathway
GO:1900181 negative regulation of protein localization to nucleus
GO:2001205 negative regulation of osteoclast development

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR003928 Claudin-18FamilyFamily
IPR004031 PMP-22/EMP/MP20/Claudin superfamilyFamilyFamily
IPR006187 ClaudinFamilyFamily
IPR017974 Claudin, conserved siteSiteConserved site

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
CLD18_HUMANPMP22_HUMANBioGRID, IntAct32296183 details
CLD18_HUMANECHP_HUMANBioGRID, IntAct32296183 details
CLD18_HUMANCLD19_HUMANDIP19706394 details