Entity Details

Primary name ABCA4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP78363
EntryNameABCA4_HUMAN
FullNameRetinal-specific phospholipid-transporting ATPase ABCA4
TaxID9606
Evidenceevidence at protein level
Length2273
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesABCA4

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0005215 transporter activity
GO:0005319 lipid transporter activity
GO:0005524 ATP binding
GO:0005548 phospholipid transporter activity
GO:0005783 endoplasmic reticulum
GO:0005887 integral component of plasma membrane
GO:0006649 phospholipid transfer to membrane
GO:0006869 lipid transport
GO:0007601 visual perception
GO:0007603 phototransduction, visible light
GO:0016020 membrane
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0043231 intracellular membrane-bounded organelle
GO:0045332 phospholipid translocation
GO:0045494 photoreceptor cell maintenance
GO:0055085 transmembrane transport
GO:0090555 phosphatidylethanolamine flippase activity
GO:0097381 photoreceptor disc membrane
GO:0140326 ATPase-coupled intramembrane lipid transporter activity
GO:0140327 flippase activity
GO:0140347 N-retinylidene-phosphatidylethanolamine flippase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum
Membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR005951 Retinal-specific ATP-binding cassette transporterFamilyFamily
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR026082 ABC transporter AFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ABCA4_HUMANCNGB1_HUMANBioGRID, HPRD10466724 details