Entity Details

Primary name TNFC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ06643
EntryNameTNFC_HUMAN
FullNameLymphotoxin-beta
TaxID9606
Evidenceevidence at protein level
Length244
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesLTB

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0010467 gene expression
GO:0016021 integral component of membrane
GO:0032735 positive regulation of interleukin-12 production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0043588 skin development
GO:0048535 lymph node development

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002961 Lymphotoxin-betaFamilyFamily
IPR006052 Tumour necrosis factor domainDomainDomain
IPR006053 Tumour necrosis factorFamilyFamily
IPR008983 Tumour necrosis factor-like domain superfamilyFamilyHomologous superfamily
IPR021184 Tumour necrosis factor, conserved siteSiteConserved site

Diseases

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