Entity Details

Primary name AMPE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ07075
EntryNameAMPE_HUMAN
FullNameGlutamyl aminopeptidase
TaxID9606
Evidenceevidence at protein level
Length957
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesENPEP

GO terms

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GOName
GO:0001525 angiogenesis
GO:0002003 angiotensin maturation
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin
GO:0004177 aminopeptidase activity
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005903 brush border
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008217 regulation of blood pressure
GO:0008270 zinc ion binding
GO:0008283 cell population proliferation
GO:0009897 external side of plasma membrane
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0031410 cytoplasmic vesicle
GO:0032835 glomerulus development
GO:0042277 peptide binding
GO:0043171 peptide catabolic process
GO:0045177 apical part of cell
GO:0070006 metalloaminopeptidase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolaseFamilyFamily
IPR014782 Peptidase M1, membrane alanine aminopeptidaseDomainDomain
IPR024571 ERAP1-like C-terminal domainDomainDomain
IPR033508 Aminopeptidase AFamilyFamily
IPR034016 Aminopeptidase N-typeFamilyFamily
IPR042097 Aminopeptidase N-like , N-terminalFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule

Interactions

3 interactions