Entity Details

Primary name NCBP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ09161
EntryNameNCBP1_HUMAN
FullNameNuclear cap-binding protein subunit 1
TaxID9606
Evidenceevidence at protein level
Length790
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesNCBP1

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000245 spliceosomal complex assembly
GO:0000339 RNA cap binding
GO:0000340 RNA 7-methylguanosine cap binding
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005845 mRNA cap binding complex
GO:0005846 nuclear cap binding complex
GO:0006366 transcription by RNA polymerase II
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0006401 RNA catabolic process
GO:0006405 RNA export from nucleus
GO:0006406 mRNA export from nucleus
GO:0006446 regulation of translational initiation
GO:0008334 histone mRNA metabolic process
GO:0008380 RNA splicing
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016070 RNA metabolic process
GO:0030307 positive regulation of cell growth
GO:0031047 gene silencing by RNA
GO:0031124 mRNA 3'-end processing
GO:0031442 positive regulation of mRNA 3'-end processing
GO:0034518 RNA cap binding complex
GO:0042795 snRNA transcription by RNA polymerase II
GO:0045292 mRNA cis splicing, via spliceosome
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0050684 regulation of mRNA processing
GO:0051168 nuclear export
GO:0098789 pre-mRNA cleavage required for polyadenylation
GO:1905216 positive regulation of RNA binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003890 MIF4G-like, type 3DomainDomain
IPR015172 MIF4G-like, type 1DomainDomain
IPR015174 MIF4G-like, type 2DomainDomain
IPR016021 MIF4G-like domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR027159 Nuclear cap-binding protein subunit 1FamilyFamily

Diseases

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Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
NCBP1_HUMANBRE1B_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
NCBP1_HUMANNCBP2_HUMANBioGRID, DIP, HPRD, IntAct, MINT11545740 12374755 12434151 17190602 19668212 22365833 22939629 23665581 24981860 26264872 26344197 26382858 26496610 29101316 29395067 29997244 31448526 31467278 32814053 32960270 7478990 9933612 details
NCBP1_HUMANTHOC4_HUMANBioGRID, IntAct, MINT17190602 18974867 19262567 23222130 32960270 details
NCBP1_HUMANPARN_HUMANMINT20379136 details
NCBP1_HUMANNCBP3_HUMANBioGRID, IntAct, MINT22365833 26382858 31448526 32960270 details
NCBP1_HUMANZDH17_HUMANBioGRID, IntAct24705354 details
NCBP1_HUMANBRE1A_HUMANBioGRID, IntAct32296183 details
NCBP1_HUMANPPIP1_HUMANBioGRID, IntAct32296183 details
NCBP1_HUMANDX39B_HUMANBioGRID, IntAct17190602 23222130 32960270 32989256 details
NCBP1_HUMANHNRPF_HUMANBioGRID, HPRD, IntAct32960270 9111328 details
NCBP1_HUMANHNRH1_HUMANBioGRID, HPRD, IntAct32960270 9111328 details
NCBP1_HUMANBNIP2_HUMANBioGRID7478990 details
NCBP1_HUMANBNIP3_HUMANBioGRID, HPRD7478990 details
NCBP1_HUMANSEC20_HUMANBioGRID, HPRD7478990 details
NCBP1_HUMANPTEN_HUMANBioGRID31685992 details
NCBP1_HUMANIF4G1_HUMANBioGRID, HPRD, IntAct11340157 15361857 25049393 details
NCBP1_HUMANIF4G3_HUMANIntAct15361857 details
NCBP1_HUMANCNBP_HUMANIntAct17353931 details
NCBP1_HUMAN1433G_HUMANIntAct17353931 details
NCBP1_HUMANGSTK1_HUMANIntAct17353931 details
NCBP1_HUMANSF3A2_HUMANBioGRID, MINT17332742 details
NCBP1_HUMANRS6_HUMANIntAct18423201 details
NCBP1_HUMANPDIP3_HUMANBioGRID, IntAct18423201 25049393 details
NCBP1_HUMANKS6B1_HUMANBioGRID, HPRD, IntAct10973943 18423201 details
NCBP1_HUMANROA1_HUMANBioGRID, IntAct, MINT19262567 22446626 32960270 details
NCBP1_HUMANPABP1_HUMANBioGRID, DIP, IntAct23665581 29395067 32960270 details
NCBP1_HUMANU2AF2_HUMANBioGRID, IntAct26641092 32960270 details
NCBP1_HUMANTHOC2_HUMANBioGRID, IntAct17190602 23222130 32960270 details
NCBP1_HUMANRU2A_HUMANHPRD, IntAct2148205 32960270 details
NCBP1_HUMANTHOC5_HUMANBioGRID17190602 details
NCBP1_HUMANTHOC1_HUMANBioGRID17190602 details
NCBP1_HUMANTHOC3_HUMANBioGRID17190602 23222130 details
NCBP1_HUMANTHOC6_HUMANBioGRID17190602 details
NCBP1_HUMAN3MG_HUMANBioGRID23537643 details
NCBP1_HUMANRUVB1_HUMANBioGRID20371770 details
NCBP1_HUMAN1433E_HUMANBioGRID19608861 details
NCBP1_HUMANLN28A_HUMANBioGRID24778252 details
NCBP1_HUMANSLBP_HUMANBioGRID27773672 28118078 details
NCBP1_HUMANMTA70_HUMANBioGRID30232453 details
NCBP1_HUMANIF4G2_HUMANHPRD15361857 details