Entity Details

Primary name BST1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ10588
EntryNameBST1_HUMAN
FullNameADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
TaxID9606
Evidenceevidence at protein level
Length318
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesBST1

GO terms

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GOName
GO:0001931 uropod
GO:0001952 regulation of cell-matrix adhesion
GO:0002691 regulation of cellular extravasation
GO:0003953 NAD+ nucleosidase activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0006959 humoral immune response
GO:0007165 signal transduction
GO:0008284 positive regulation of cell population proliferation
GO:0016740 transferase activity
GO:0016849 phosphorus-oxygen lyase activity
GO:0019674 NAD metabolic process
GO:0019898 extrinsic component of membrane
GO:0030890 positive regulation of B cell proliferation
GO:0031225 anchored component of membrane
GO:0032956 regulation of actin cytoskeleton organization
GO:0035579 specific granule membrane
GO:0043312 neutrophil degranulation
GO:0050135 NAD(P)+ nucleosidase activity
GO:0050727 regulation of inflammatory response
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0050848 regulation of calcium-mediated signaling
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0061811 ADP-ribosyl cyclase activity
GO:0061812 cyclic ADP-ribose hydrolase
GO:0070062 extracellular exosome
GO:0090022 regulation of neutrophil chemotaxis
GO:0090322 regulation of superoxide metabolic process
GO:2001044 regulation of integrin-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003193 ADP-ribosyl cyclase (CD38/157)FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB02483 Etheno-NADDrugbanksmall molecule
DB02701 NicotinamideDrugbanksmall molecule
DB02930 Adenosine 5'-[gamma-thio]triphosphateDrugbanksmall molecule
DB03227 Nicotinamide MononucleotideDrugbanksmall molecule
DB03732 Etheno-NadpDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
BST1_HUMANLBP_HUMANBioGRID, IntAct21988832 details
BST1_HUMANBST1_HUMANBioGRID, HPRD11439087 11866528 details
BST1_HUMANCAV1_HUMANHPRD11866528 details