Entity Details

Primary name GDF11
Entity type gene
Source Source Link

Details

PrimaryID10220
RefseqGene
SymbolGDF11
Namegrowth differentiation factor 11
Chromosome12
Location12q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-07
ModificationDate2021-06-19

Ontological Relatives

UniProt IDsGDF11_HUMAN

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001656 metanephros development
GO:0001657 ureteric bud development
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0007399 nervous system development
GO:0007498 mesoderm development
GO:0008083 growth factor activity
GO:0008285 negative regulation of cell population proliferation
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0021512 spinal cord anterior/posterior patterning
GO:0031016 pancreas development
GO:0032991 protein-containing complex
GO:0043231 intracellular membrane-bounded organelle
GO:0045665 negative regulation of neuron differentiation
GO:0048469 cell maturation
GO:0048593 camera-type eye morphogenesis
GO:0060021 roof of mouth development
GO:0060395 SMAD protein signal transduction

Diseases

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Interactions

19 interactions

InteractorPartnerSourcesPublicationsLink
GDF11ACVR2BHPRD, MINT16845371 21054789 details
GDF11WFIKKN2IntAct18596030 details
GDF11WFIKKN1IntAct18596030 details
GDF11SCGB2A2BioGRID, IntAct28514442 details
GDF11BMP7BioGRID, IntAct28514442 details
GDF11APPBioGRID, IntAct28514442 details
GDF11LYPD4BioGRID, IntAct28514442 details
GDF11TMEM25BioGRID, IntAct26186194 28514442 details
GDF11TDGF1BioGRID, IntAct28514442 details
GDF11CRPBioGRID, IntAct28514442 details
GDF11DKK3BioGRID, IntAct28514442 details
GDF11PCDHGA5BioGRID, IntAct28514442 details
GDF11SIAEBioGRID, IntAct26186194 28514442 details
GDF11LIPHBioGRID, IntAct26186194 28514442 details
GDF11PRSS2BioGRID, IntAct28514442 details
GDF11ANTXR1BioGRID26186194 details
GDF11ERLEC1BioGRID26186194 details
GDF11PRC1BioGRID31586073 details
GDF11MKRN2BioGRID32460013 details