Entity Details

Primary name EGLN2
Entity type gene
Source Source Link

Details

PrimaryID112398
RefseqGene
SymbolEGLN2
Nameegl-9 family hypoxia inducible factor 2
Chromosome19
Location19q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsEGLN2_HUMAN

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0001666 response to hypoxia
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0008198 ferrous iron binding
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0019826 oxygen sensor activity
GO:0030520 intracellular estrogen receptor signaling pathway
GO:0031418 L-ascorbic acid binding
GO:0031543 peptidyl-proline dioxygenase activity
GO:0031545 peptidyl-proline 4-dioxygenase activity
GO:0043523 regulation of neuron apoptotic process
GO:0045454 cell redox homeostasis
GO:0045732 positive regulation of protein catabolic process
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 cellular response to hypoxia

Diseases

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Interactions

38 interactions

InteractorPartnerSourcesPublicationsLink
EGLN2HIF1ABioGRID, HPRD, IntAct, MINT11292861 11292862 15474027 16155211 16511565 17353276 18264140 26644182 details
EGLN2MOB4HPRD, IntAct16169070 details
EGLN2SRPK2BioGRID, IntAct23602568 details
EGLN2EPAS1BioGRID, HPRD, IntAct15474027 17353276 23275444 details
EGLN2MFHAS1BioGRID, IntAct29513927 details
EGLN2PCNAUniProt26030842 details
EGLN2A2MBioGRID21163940 details
EGLN2TENT5ABioGRID, HPRD15231748 details
EGLN2SPOPBioGRID28089830 details
EGLN2ATF4BioGRID21951999 details
EGLN2CDK2BioGRID26644182 details
EGLN2PRKCABioGRID18710826 details
EGLN2POLR2ABioGRID18285459 details
EGLN2SIAH2BioGRID15210114 16958618 details
EGLN2EGLN3BioGRID16958618 details
EGLN2EGLN2BioGRID16958618 details
EGLN2PRPF19BioGRID20599946 details
EGLN2SPRY2BioGRID22006925 details
EGLN2LIMD1BioGRID22286099 details
EGLN2AJUBABioGRID22286099 details
EGLN2WTIPBioGRID22286099 details
EGLN2TRIP6BioGRID22286099 details
EGLN2LPPBioGRID22286099 details
EGLN2MAGEA11BioGRID19147576 details
EGLN2CEP192BioGRID23932902 26644182 details
EGLN2DYRK1ABioGRID26735018 details
EGLN2DYRK1BBioGRID26735018 details
EGLN2CUL3BioGRID28089830 details
EGLN2FBXW7BioGRID28036276 details
EGLN2CDK4BioGRID26644182 details
EGLN2CDK6BioGRID26644182 details
EGLN2RUNX3BioGRID23542169 details
EGLN2BRD4BioGRID31239290 details
EGLN2HIF3AHPRD15474027 details
EGLN2VHLIntAct17986458 details
EGLN2TRIM25BioGRID29117863 details
EGLN2HNRNPH1BioGRID26760575 details
EGLN2DDX58BioGRID32513696 details