Entity Details

Primary name GBP5
Entity type gene
Source Source Link

Details

PrimaryID115362
RefseqGeneNG_052816
SymbolGBP5
Nameguanylate binding protein 5
Chromosome1
Location1p22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-10-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGBP5_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0006954 inflammatory response
GO:0016020 membrane
GO:0031410 cytoplasmic vesicle
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032741 positive regulation of interleukin-18 production
GO:0034067 protein localization to Golgi apparatus
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0045089 positive regulation of innate immune response
GO:0048471 perinuclear region of cytoplasm
GO:0051289 protein homotetramerization
GO:0071346 cellular response to interferon-gamma
GO:1900017 positive regulation of cytokine production involved in inflammatory response
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly

Diseases

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Interactions

16 interactions

InteractorPartnerSourcesPublicationsLink
GBP5GBP5BioGRID, HPRD, IntAct, MINT, UniProt16189514 20180847 21151871 details
GBP5GBP1BioGRID, IntAct, UniProt21151871 28514442 details
GBP5ADRB2BioGRID, MINT28298427 details
GBP5GBP2UniProt21151871 details
GBP5GBP3UniProt21151871 details
GBP5GBP4UniProt21151871 details
GBP5SLC22A16BioGRID, IntAct28514442 details
GBP5CPEB1BioGRID, IntAct28514442 details
GBP5EPHA4BioGRID, IntAct28514442 details
GBP5APOL2BioGRID, IntAct28514442 details
GBP5C1orf159BioGRID, IntAct28514442 details
GBP5SURF1BioGRID, IntAct28514442 details
GBP5ACSM1BioGRID, IntAct28514442 details
GBP5IMMTBioGRID, IntAct30021884 details
GBP5LCA5LBioGRID, IntAct30021884 details
GBP5STT3BBioGRID, IntAct30021884 details