Entity Details

Primary name PD2R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13258
EntryNamePD2R_HUMAN
FullNameProstaglandin D2 receptor
TaxID9606
Evidenceevidence at transcript level
Length359
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTGDR

GO terms

Show/Hide Table
GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004956 prostaglandin D receptor activity
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0016021 integral component of membrane
GO:0043303 mast cell degranulation

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000376 Prostaglandin D receptorFamilyFamily
IPR008365 Prostanoid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

Show/Hide Table
Disease IDSourceNameDescription
607277 OMIMAsthma-related traits 1 (ASRT1)Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis. Disease susceptibility is associated with variants affecting the gene represented in this entry.

Drugs

Show/Hide Table
DrugNameSourceType
DB00716 NedocromilDrugbanksmall molecule