Entity Details

Primary name TICAM1
Entity type gene
Source Source Link

Details

PrimaryID148022
RefseqGeneNG_031998
SymbolTICAM1
Nametoll like receptor adaptor molecule 1
Chromosome19
Location19p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTCAM1_HUMAN

GO terms

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GOName
GO:0002281 macrophage activation involved in immune response
GO:0002735 positive regulation of myeloid dendritic cell cytokine production
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0005739 mitochondrion
GO:0005776 autophagosome
GO:0005829 cytosol
GO:0006954 inflammatory response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0010008 endosome membrane
GO:0010508 positive regulation of autophagy
GO:0010628 positive regulation of gene expression
GO:0016032 viral process
GO:0019901 protein kinase binding
GO:0030890 positive regulation of B cell proliferation
GO:0031398 positive regulation of protein ubiquitination
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032092 positive regulation of protein binding
GO:0032722 positive regulation of chemokine production
GO:0032728 positive regulation of interferon-beta production
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032816 positive regulation of natural killer cell activation
GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway
GO:0034138 toll-like receptor 3 signaling pathway
GO:0035666 TRIF-dependent toll-like receptor signaling pathway
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043254 regulation of protein-containing complex assembly
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051607 defense response to virus
GO:0070266 necroptotic process
GO:0071222 cellular response to lipopolysaccharide
GO:0097190 apoptotic signaling pathway
GO:0097342 ripoptosome
GO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus
GO:1900017 positive regulation of cytokine production involved in inflammatory response

Diseases

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Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
TICAM1TICAM2BioGRID, HPRD, IntAct12721283 14519765 25736436 31511519 details
TICAM1SRSF4BioGRID, IntAct21988832 details
TICAM1SARM1IntAct26592460 details
TICAM1TRAF2BioGRID14982987 19795416 20047764 details
TICAM1TRAF6BioGRID, HPRD14530355 14982987 15474016 19795416 20047764 24812060 25736436 details
TICAM1UBQLN1BioGRID21695056 details
TICAM1TRAF1BioGRID, HPRD14982987 16323247 19795416 details
TICAM1TLR3BioGRID, HPRD12539043 14982987 25736436 27810922 31511519 details
TICAM1IRF3BioGRID, HPRD14739303 25636800 details
TICAM1TRIM8BioGRID28747347 details
TICAM1IRF7HPRD14739303 details
TICAM1TNFAIP3BioGRID, HPRD, MINT15474016 details
TICAM1PIAS4BioGRID, HPRD, MINT15251447 details
TICAM1TMED7-TICAM2IntAct12721283 details
TICAM1TBK1BioGRID, DIP, HPRD, IntAct, UniProt14530355 15841462 19416887 19656901 21903422 25736436 28049150 28747347 31511519 details
TICAM1TRIM56BioGRID, IntAct22948160 details
TICAM1RIPK1BioGRID, HPRD15064760 19734906 25736436 33052227 details
TICAM1RIPK3BioGRID, HPRD15064760 details
TICAM1RNF216BioGRID16968706 details
TICAM1TLR4BioGRID19656901 25736436 31511519 details
TICAM1CBLBBioGRID20639876 details
TICAM1TRAF3BioGRID, HPRD14982987 16306936 16306937 17991829 24577058 28747347 31511519 details
TICAM1TRAF5BioGRID14982987 details
TICAM1TRAF4BioGRID, HPRD16052631 details
TICAM1MAVSBioGRID, HPRD16153868 details
TICAM1TRIM38BioGRID23056470 details
TICAM1SYKBioGRID23962979 details
TICAM1TICAM1BioGRID24577058 details
TICAM1CASP8BioGRID21737330 33052227 details
TICAM1CFLARBioGRID21737330 details
TICAM1FOSL1BioGRID28049150 details
TICAM1ABCF1BioGRID30770245 details
TICAM1USP19BioGRID31511519 details
TICAM1KCTD10BioGRID31511519 details
TICAM1RNF144BBioGRID31509299 details
TICAM1PELI1BioGRID33052227 details
TICAM1TRAM1HPRD12721283 details
TICAM1PIK3CAHPRD15940673 details
TICAM1TLR2HPRD12471095 details
TICAM1IKBKEHPRD12692549 details
TICAM1TIRAPHPRD14517278 details
TICAM1AZI2HPRD15611223 details
TICAM1TANKBioGRID, IntAct21903422 details
TICAM1CDCA5BioGRID, IntAct26496610 details
TICAM1KIF21BBioGRID, IntAct26496610 details
TICAM1MKNK2BioGRID, IntAct26496610 details
TICAM1CARM1BioGRID, IntAct26186194 28514442 details
TICAM1XPO1BioGRID26673895 details
TICAM1TRIM25BioGRID29117863 details
TICAM1DDX58BioGRID32513696 details