Entity Details

Primary name APLF
Entity type gene
Source Source Link

Details

PrimaryID200558
RefseqGene
SymbolAPLF
Nameaprataxin and PNKP like factor
Chromosome2
Location2p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-04-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAPLF_HUMAN

GO terms

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GOName
GO:0000012 single strand break repair
GO:0000166 nucleotide binding
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004520 endodeoxyribonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006302 double-strand break repair
GO:0006974 cellular response to DNA damage stimulus
GO:0008408 3'-5' exonuclease activity
GO:0035861 site of double-strand break
GO:0046872 metal ion binding
GO:0051106 positive regulation of DNA ligation

Diseases

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Interactions

43 interactions

InteractorPartnerSourcesPublicationsLink
APLFXRCC1BioGRID, HPRD, IntAct, MINT17353262 17396150 23178593 26186194 27067600 28514442 details
APLFXRCC4BioGRID, HPRD, IntAct, MINT17353262 17396150 23178593 26186194 28514442 details
APLFPARP1BioGRID, DIP, IntAct, MINT17396150 18172500 20098424 26186194 27067600 28514442 details
APLFXRCC5BioGRID, DIP, IntAct, MINT17396150 20098424 23178593 26186194 28514442 details
APLFLIG4BioGRID, HPRD, IntAct, MINT17396150 23178593 26186194 28514442 details
APLFPARP2BioGRID, IntAct, MINT21812934 26186194 28514442 details
APLFAPPBioGRID21832049 details
APLFFBXO25BioGRID23940030 details
APLFGMCL1BioGRID25416956 details
APLFXRCC6BioGRID, IntAct, MINT17396150 23178593 26186194 27067600 28514442 details
APLFCHD1LBioGRID, IntAct19661379 23926104 26186194 28514442 details
APLFMACROH2A1BioGRID, IntAct26186194 27067600 28514442 details
APLFH3-4BioGRID21211722 27067600 details
APLFH2AC20BioGRID27067600 details
APLFAPLFHPRD17396150 details
APLFIRX5HPRD17396150 details
APLFRPA1MINT17396150 details
APLFRECQLMINT17396150 details
APLFTOP1BioGRID, MINT17396150 26186194 details
APLFLIG3BioGRID, IntAct, MINT17396150 26186194 28514442 details
APLFRPS3AMINT17396150 details
APLFPRKDCMINT17396150 details
APLFYBX1Molecular Connections22118625 details
APLFH2BC1BioGRID, IntAct26186194 28514442 details
APLFSUPT16HBioGRID, IntAct26186194 28514442 details
APLFMACROH2A2BioGRID, IntAct26186194 28514442 details
APLFTDP1BioGRID, IntAct26186194 28514442 details
APLFZG16BBioGRID, IntAct26186194 28514442 details
APLFH2AC21BioGRID, IntAct26186194 28514442 details
APLFHLTFBioGRID, IntAct26186194 28514442 details
APLFSSRP1BioGRID, IntAct26186194 28514442 details
APLFXPCBioGRID, IntAct26186194 28514442 details
APLFCETN2BioGRID, IntAct26186194 28514442 details
APLFMSH3BioGRID, IntAct28514442 details
APLFH2AC13IntAct28514442 details
APLFH2AC15IntAct28514442 details
APLFH2AC16IntAct28514442 details
APLFH2AC17IntAct28514442 details
APLFH2AC11BioGRID, IntAct26186194 28514442 details
APLFCST1BioGRID, IntAct28514442 details
APLFCST4BioGRID, IntAct26186194 28514442 details
APLFPOLBBioGRID, IntAct26186194 28514442 details
APLFH2BC11BioGRID26186194 details