Entity Details

Primary name EPRS1
Entity type gene
Source Source Link

Details

PrimaryID2058
RefseqGene
SymbolEPRS1
Nameglutamyl-prolyl-tRNA synthetase 1
Chromosome1
Location1q41
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-12-09
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSYEP_HUMAN

GO terms

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GOName
GO:0004818 glutamate-tRNA ligase activity
GO:0004827 proline-tRNA ligase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0006433 prolyl-tRNA aminoacylation
GO:0008270 zinc ion binding
GO:0016020 membrane
GO:0017101 aminoacyl-tRNA synthetase multienzyme complex
GO:0017148 negative regulation of translation
GO:0032869 cellular response to insulin stimulus
GO:0035613 RNA stem-loop binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0051020 GTPase binding
GO:0065003 protein-containing complex assembly
GO:0071346 cellular response to interferon-gamma
GO:0097452 GAIT complex
GO:0140212 regulation of long-chain fatty acid import into cell
GO:1990904 ribonucleoprotein complex

Diseases

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Interactions

245 interactions

InteractorPartnerSourcesPublicationsLink
EPRS1IARS1BioGRID, HPRD, IntAct, MINT, UniProt10913161 11142386 22863883 22939629 26344197 30021884 9556618 details
EPRS1HSP90AA1BioGRID, HPRD, MINT10913161 details
EPRS1ARL4DBioGRID, HPRD, IntAct16169070 details
EPRS1NELFCDBioGRID, HPRD, IntAct16169070 details
EPRS1EEF1DBioGRID, IntAct20195357 details
EPRS1RARS1BioGRID, HPRD, IntAct22939629 26344197 28514442 31536960 9556618 details
EPRS1TAB1BioGRID, MINT21900206 details
EPRS1ESR1BioGRID, IntAct20348541 25604459 details
EPRS1DUX4BioGRID, IntAct26816005 details
EPRS1HSCBBioGRID, DIP, IntAct24606901 28380382 details
EPRS1EPRS1DIP23263184 details
EPRS1NEDD4BioGRID16055720 details
EPRS1CDC42BioGRID22863883 31478661 details
EPRS1PTENBioGRID31685992 details
EPRS1SUMO2BioGRID32786267 details
EPRS1NFKBIBIntAct14743216 details
EPRS1NFKBIEIntAct14743216 details
EPRS1IKBKBIntAct14743216 details
EPRS1NFKB2IntAct14743216 details
EPRS1MAP3K14IntAct14743216 details
EPRS1RELAIntAct14743216 details
EPRS1RELBIntAct14743216 details
EPRS1RIPK3IntAct14743216 details
EPRS1MAP3K7IntAct14743216 details
EPRS1ATG12IntAct17353931 details
EPRS1YWHAZMINT15161933 details
EPRS1ETS1IntAct20195357 details
EPRS1MAP1LC3ABioGRID, IntAct20562859 22963397 details
EPRS1SYNCRIPDIP, HPRD, IntAct15479637 21220307 22386318 details
EPRS1KARS1BioGRID, DIP, IntAct21220307 22386318 22751010 22939629 26344197 28514442 31536960 details
EPRS1AIMP2BioGRID, DIP, HPRD18695251 22939629 26344197 31792442 9878398 details
EPRS1HDAC5BioGRID21081666 details
EPRS1ITGA4BioGRID22623428 details
EPRS1EGFRBioGRID23956138 details
EPRS1RNF126BioGRID26508657 details
EPRS1U2AF2BioGRID26641092 details
EPRS1C1orf131BioGRID26472760 details
EPRS1MYO6BioGRID26950368 details
EPRS1ISG15BioGRID33024031 details
EPRS1DUS2HPRD15994936 details
EPRS1TFE3BioGRID, IntAct17353931 details
EPRS1MCCBioGRID, IntAct17353931 details
EPRS1IKBKEBioGRID, IntAct17353931 details
EPRS1AGO1MINT17932509 details
EPRS1AGO2MINT17932509 details
EPRS1BAG2MINT18457437 details
EPRS1MAPK13IntAct19135240 details
EPRS1GABARAPL2IntAct20562859 details
EPRS1VCAM1BioGRID, IntAct19738201 22623428 details
EPRS1CUL1BioGRID, IntAct21145461 details
EPRS1COPS5BioGRID, IntAct21145461 details
EPRS1CUL3BioGRID, IntAct21145461 details
EPRS1LRRK2BioGRID, IntAct17400507 31046837 details
EPRS1ESR2BioGRID, IntAct25604459 29509190 details
EPRS1JUNMINT25609649 details
EPRS1PKN2BioGRID, IntAct26496610 details
EPRS1BCAR1bhf-ucl28007913 details
EPRS1PLEKHA7IntAct28877994 details
EPRS1SDCBPBioGRID, IntAct26186194 28514442 details
EPRS1AIMP1BioGRID, IntAct22939629 26344197 28514442 details
EPRS1LARS1BioGRID, IntAct22863883 22939629 26344197 27684187 28514442 details
EPRS1QARS1BioGRID, IntAct22939629 26344197 28514442 details
EPRS1CDK5DIP21220307 details
EPRS1BET1BioGRID, IntAct29568061 details
EPRS1DLDBioGRID, IntAct29128334 details
EPRS1DLSTBioGRID, IntAct29128334 details
EPRS1SDHABioGRID, IntAct29128334 details
EPRS1SOAT1BioGRID, IntAct29128334 details
EPRS1SOD1BioGRID, IntAct29128334 details
EPRS1SMARCB1IntAct30108113 details
EPRS1STK38LIntAct30108113 details
EPRS1MAPTUniProt26269332 details
EPRS1H3-4BioGRID, IntAct30021884 details
EPRS1H2BC21BioGRID, IntAct30021884 details
EPRS1NPM1BioGRID, IntAct30021884 details
EPRS1PDCD11BioGRID, IntAct30021884 details
EPRS1DTX4BioGRID, IntAct30021884 details
EPRS1CFTRBioGRID, IntAct26618866 29924966 details
EPRS1ZDHHC5UniProt31402609 details
EPRS1RIN3BioGRID, IntAct32552912 details
EPRS1NDNBioGRID, MINT32529326 details
EPRS1TAGLNMINT32774160 details
EPRS1CDK2BioGRID21319273 details
EPRS1DARS1BioGRID22939629 26344197 details
EPRS1MARS1BioGRID22939629 26344197 details
EPRS1EEF1E1BioGRID22939629 26344197 details
EPRS1GARS1BioGRID22939629 26344197 details
EPRS1RPL6BioGRID22939629 details
EPRS1TCP1BioGRID22939629 details
EPRS1SF3B1BioGRID22939629 details
EPRS1NARS1BioGRID22939629 details
EPRS1SRSF10BioGRID22939629 details
EPRS1TRMT1BioGRID22939629 details
EPRS1TXLNABioGRID22939629 details
EPRS1LAMP2BioGRID22939629 details
EPRS1VBP1BioGRID22939629 details
EPRS1TUBBBioGRID22939629 details
EPRS1UBA1BioGRID22939629 details
EPRS1DDX42BioGRID22939629 details
EPRS1ASNSBioGRID22939629 26344197 details
EPRS1XPO1BioGRID22939629 26344197 details
EPRS1ATP6V1B2BioGRID22939629 details
EPRS1DDX5BioGRID22939629 details
EPRS1PFKPBioGRID22939629 details
EPRS1FN1BioGRID19738201 details
EPRS1FBXO6BioGRID22268729 details
EPRS1CMYA5BioGRID22863883 details
EPRS1LRRC47BioGRID22863883 details
EPRS1LRRFIP1BioGRID22863883 details
EPRS1ELOBBioGRID22863883 details
EPRS1TESBioGRID22863883 details
EPRS1VPS25BioGRID22863883 details
EPRS1IGF2BP3BioGRID22863883 details
EPRS1PTBP1BioGRID22863883 details
EPRS1RFC4BioGRID22863883 details
EPRS1RPL23ABioGRID22863883 details
EPRS1RPA3BioGRID24332808 details
EPRS1RPA2BioGRID24332808 details
EPRS1RPA1BioGRID24332808 details
EPRS1LGR4BioGRID24639526 details
EPRS1STAU1BioGRID23125841 details
EPRS1AURKABioGRID23443559 details
EPRS1HUWE1BioGRID25147182 details
EPRS1CUL7BioGRID24711643 details
EPRS1CCDC8BioGRID24711643 details
EPRS1EZH2BioGRID24457600 details
EPRS1SUZ12BioGRID24457600 details
EPRS1RNF2BioGRID24457600 details
EPRS1COMTD1BioGRID26186194 details
EPRS1FBXW11BioGRID25515538 details
EPRS1ATAD3BBioGRID26344197 details
EPRS1CANXBioGRID26344197 details
EPRS1CLGNBioGRID26344197 details
EPRS1ABCB7BioGRID26344197 details
EPRS1AHSA1BioGRID26344197 details
EPRS1CADBioGRID26344197 details
EPRS1CIAPIN1BioGRID26344197 details
EPRS1CLTCL1BioGRID26344197 details
EPRS1PARS2BioGRID26344197 31536960 details
EPRS1IDH3ABioGRID26344197 details
EPRS1IPO9BioGRID26344197 details
EPRS1KDSRBioGRID26344197 details
EPRS1NCLNBioGRID26344197 details
EPRS1NMD3BioGRID26344197 details
EPRS1PSMD2BioGRID26344197 details
EPRS1RPN2BioGRID26344197 details
EPRS1STOMBioGRID26344197 details
EPRS1TARS3BioGRID26344197 details
EPRS1TRMT6BioGRID26344197 details
EPRS1NTRK1BioGRID25921289 details
EPRS1CRY1BioGRID25756610 details
EPRS1CRY2BioGRID25756610 details
EPRS1CDC73BioGRID27462432 details
EPRS1CYLDBioGRID27591049 details
EPRS1VDAC1BioGRID29128334 details
EPRS1BRCA1BioGRID26831064 details
EPRS1YAP1BioGRID25796446 details
EPRS1ZNF598BioGRID28685749 details
EPRS1FBXO7BioGRID27503909 details
EPRS1TMPOBioGRID28902428 details
EPRS1PTCH1BioGRID26885983 details
EPRS1ACO2BioGRID27684187 details
EPRS1HSPA8BioGRID27684187 details
EPRS1PPP6CBioGRID27684187 details
EPRS1BRAFBioGRID27684187 details
EPRS1HDAC4BioGRID27684187 details
EPRS1KRASBioGRID27684187 details
EPRS1TGFB1BioGRID27684187 details
EPRS1RAD18BioGRID27377895 details
EPRS1PRPF8BioGRID28515276 details
EPRS1EFTUD2BioGRID28515276 details
EPRS1AAR2BioGRID28515276 details
EPRS1PIH1D1BioGRID28515276 details
EPRS1CHD3BioGRID28977666 details
EPRS1CHD4BioGRID28977666 details
EPRS1LARP7BioGRID26725010 29845934 details
EPRS1CDC34BioGRID29564676 details
EPRS1SPDL1BioGRID30258100 details
EPRS1RIOK1BioGRID21081503 details
EPRS1HEXIM1BioGRID29845934 details
EPRS1MEPCEBioGRID29845934 details
EPRS1RNF123BioGRID29676528 details
EPRS1HECTD1BioGRID29511261 details
EPRS1SNAI1BioGRID29331416 details
EPRS1AGR2BioGRID30575818 details
EPRS1RECQL4BioGRID29229926 details
EPRS1RNF144ABioGRID29212245 details
EPRS1MYCBioGRID29467282 details
EPRS1H4C1BioGRID27248496 30804502 details
EPRS1H2BC3BioGRID27248496 details
EPRS1H2AC4BioGRID27248496 details
EPRS1GRWD1BioGRID29991511 details
EPRS1VIRMABioGRID29507755 details
EPRS1ACTC1BioGRID30890647 details
EPRS1PHBBioGRID27025967 details
EPRS1FAF1BioGRID28443643 details
EPRS1TMEM41BBioGRID30352685 details
EPRS1NR2C2BioGRID30463901 details
EPRS1UBQLN2BioGRID30442662 details
EPRS1ATXN3BioGRID30455355 details
EPRS1DLATBioGRID31536960 details
EPRS1HACD3BioGRID31536960 details
EPRS1HSD17B4BioGRID31536960 details
EPRS1ILF3BioGRID31536960 details
EPRS1LRPPRCBioGRID31536960 details
EPRS1SND1BioGRID31536960 details
EPRS1PDHXBioGRID31536960 details
EPRS1ITFG1BioGRID25437307 details
EPRS1ARAFBioGRID29777862 details
EPRS1ABCC6BioGRID29704455 details
EPRS1BIRC3BioGRID30948266 details
EPRS1LMBR1LBioGRID31073040 details
EPRS1NFX1BioGRID31059266 details
EPRS1WWP2BioGRID31048545 details
EPRS1MATR3BioGRID29511296 details
EPRS1SQSTM1BioGRID30581152 details
EPRS1PLEKHA4BioGRID31091453 details
EPRS1PINK1BioGRID31300519 details
EPRS1ZC3H18BioGRID29298432 details
EPRS1EMC2BioGRID27342126 details
EPRS1EMC4BioGRID27342126 details
EPRS1LRRC31BioGRID33005030 details
EPRS1ANLNBioGRID31586073 details
EPRS1CHMP4BBioGRID31586073 details
EPRS1CHMP4CBioGRID31586073 details
EPRS1ECT2BioGRID31586073 details
EPRS1KIF14BioGRID31586073 details
EPRS1KIF23BioGRID31586073 details
EPRS1BRD4BioGRID31239290 details
EPRS1RMC1BioGRID33144569 details
EPRS1RBM39BioGRID28302793 details
EPRS1FBP1BioGRID32041737 details
EPRS1LGALS9BioGRID31995728 details
EPRS1DZIP3BioGRID32460013 details
EPRS1MKRN1BioGRID32460013 details
EPRS1MKRN2BioGRID32460013 details
EPRS1RBBP6BioGRID32460013 details
EPRS1GLE1BioGRID32460013 details
EPRS1BAG5BioGRID32850835 details
EPRS1PRKNBioGRID32929329 details
EPRS1UFL1BioGRID32807901 details
EPRS1DDRGK1BioGRID32807901 details
EPRS1TP53BioGRID32807901 details
EPRS1SEPTIN10BioGRID34079125 details
EPRS1NXF1BioGRID22658674 details