Entity Details

Primary name GATA4
Entity type gene
Source Source Link

Details

PrimaryID2626
RefseqGeneNG_008177
SymbolGATA4
NameGATA binding protein 4
Chromosome8
Location8p23.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-06-15
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsGATA4_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001216 DNA-binding transcription activator activity
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001947 heart looping
GO:0003162 atrioventricular node development
GO:0003180 aortic valve morphogenesis
GO:0003190 atrioventricular valve formation
GO:0003197 endocardial cushion development
GO:0003208 cardiac ventricle morphogenesis
GO:0003215 cardiac right ventricle morphogenesis
GO:0003281 ventricular septum development
GO:0003289 atrial septum primum morphogenesis
GO:0003290 atrial septum secundum morphogenesis
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007267 cell-cell signaling
GO:0007492 endoderm development
GO:0007596 blood coagulation
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0009612 response to mechanical stimulus
GO:0010507 negative regulation of autophagy
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0016604 nuclear body
GO:0019901 protein kinase binding
GO:0030513 positive regulation of BMP signaling pathway
GO:0033189 response to vitamin A
GO:0035054 embryonic heart tube anterior/posterior pattern specification
GO:0036302 atrioventricular canal development
GO:0042060 wound healing
GO:0042493 response to drug
GO:0043565 sequence-specific DNA binding
GO:0045165 cell fate commitment
GO:0045766 positive regulation of angiogenesis
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048617 embryonic foregut morphogenesis
GO:0051525 NFAT protein binding
GO:0051891 positive regulation of cardioblast differentiation
GO:0051896 regulation of protein kinase B signaling
GO:0060290 transdifferentiation
GO:0060413 atrial septum morphogenesis
GO:0060575 intestinal epithelial cell differentiation
GO:0061026 cardiac muscle tissue regeneration
GO:0061049 cell growth involved in cardiac muscle cell development
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070410 co-SMAD binding
GO:0071333 cellular response to glucose stimulus
GO:0086004 regulation of cardiac muscle cell contraction
GO:0090575 RNA polymerase II transcription regulator complex
GO:1903202 negative regulation of oxidative stress-induced cell death
GO:1990837 sequence-specific double-stranded DNA binding
GO:2001234 negative regulation of apoptotic signaling pathway

Diseases

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Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
GATA4NKX2-5BioGRID, HPRD, IntAct10075728 10948187 12845333 15542826 9312027 details
GATA4ALX4BioGRID, IntAct20211142 details
GATA4MDC1BioGRID14578343 details
GATA4HAND2BioGRID, HPRD11994297 details
GATA4NR5A1BioGRID, HPRD10446911 details
GATA4ZFPM2BioGRID, HPRD10801815 11297508 18252717 9927675 details
GATA4SRFBioGRID, HPRD11003651 11158291 details
GATA4MAPK1BioGRID11585926 details
GATA4ID1BioGRID16556596 details
GATA4ID2BioGRID16556596 details
GATA4ID3BioGRID16556596 details
GATA4EP300BioGRID, HPRD11481322 18252717 27208796 details
GATA4SP1BioGRID14988427 21184844 details
GATA4JARID2BioGRID, HPRD15542826 22215809 details
GATA4RACK1BioGRID27208796 details
GATA4NFATC4HPRD9568714 details
GATA4KLF13MINT17053787 details
GATA4EZH2BioGRID, IntAct22094255 22215809 details
GATA4TBX5BioGRID, HPRD12845333 details
GATA4HDAC2BioGRID20833366 details
GATA4EZH1BioGRID22215809 details
GATA4SUZ12BioGRID22215809 details
GATA4KDM6ABioGRID22192413 details
GATA4MEF2CHPRD10790371 details
GATA4CRIP2HPRD12530967 details
GATA4MAPK3HPRD11585926 details
GATA4MED1HPRD11724781 details
GATA4PIAS1HPRD15337742 details
GATA4FOSHPRD9207128 details
GATA4FOXE1BioGRID, MINT25609649 details
GATA4KSR1IntAct27086506 details
GATA4H1-5BioGRID, IntAct30021884 details
GATA4ARHGEF19BioGRID, IntAct32203420 details
GATA4SOX2BioGRID28794006 details
GATA4SP100BioGRID31753913 details
GATA4DNMT1IntAct22094255 details
GATA4DNMT3BIntAct22094255 details
GATA4H2AXIntAct22094255 details
GATA4SIRT1IntAct22094255 details
GATA4CYP2C19IntAct20206639 details