Entity Details

Primary name TRYB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15661
EntryNameTRYB1_HUMAN
FullNameTryptase alpha/beta-1
TaxID9606
Evidenceevidence at protein level
Length275
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesTPSAB1

GO terms

Show/Hide Table
GOName
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0006952 defense response
GO:0008236 serine-type peptidase activity
GO:0022617 extracellular matrix disassembly
GO:0042802 identical protein binding

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB06848 1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamineDrugbanksmall molecule
DB06849 1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamineDrugbanksmall molecule

Interactions

4 interactions